COMMON ESTROGEN REPLACEMENT THERAPY PRODUCTS
IN THE UNITED STATES

DRUG CLASS DRUG NAME INGREDIENTS DRUG SOURCE ROUTE YRS. ON MKT.
Plant-Based Climara 17 B-estradiol yam transdermal 2
Plant-Based *Estrace 17 B-estradiol soybean, yam oral
Vaginal
22
10
Plant-Based Estraderm 17 B-estradiol yam transdermal 11
Plant-Based Estratab estrone sulfate (75-85%),
equilin sulfate (6-15%),
equilenin,
17 a-dihydroequilin,
17 a-estradiol,
17 a-dihydroequilenin
soybean, yam oral 20
Plant-Based Estring 17 B-estradiol yam vaginal ring 2
Plant-Based Menest Same as in Estratab yam oral 20
Plant-Based *Ogen estropipate (estrone) yam oral
Vaginal
40
3
Plant-Based *Ortho-EST estropipate (estrone) yam oral 4
Plant-Based Vivelle 17 B-estradiol yam transdermal 2
Synthetic Alora 17 B-estradiol synthetic transdermal 1
Synthetic Estinyl ethinyl estradiol synthetic oral 30
Synthetic Fempatch 17 B-estradiol synthetic transdermal 1
Synthetic Ortho-Dienestrol dienstrol synthetic vaginal 20
Estrogen/Androgen Combination Estratest HS Estratest Same as in Estratab, plus methyltestosterone plant + synthetic oral 9

Progestationals may be used adjunctively to minimize risk of endometrial cancer. *Lower-cost generic equivalents are available for some brand-name HRT drugs. "All approved estrogen drug products carry substantially the same labeling text because of their substantially similar safety and effectiveness profile in humans." FDA, May 22, 1995. The FDA has not approved any form of HRT for the prevention of heart disease because the studies conducted to date have been observational only and do not measure up to the standards typically used to prove a drug is effective.
The above estrogen alternatives appears here in part from "Facts About Hormone Replacement Therapy," a comprehensive brochure prepared by the Humane Society of the United States as a public service. Individuals may obtain the complete chart of estrogen alternatives free by sending a #10 self-addressed stamped envelope to: Estrogen Alternatives, The HSUS, 2100 "L" St. NW, Washington, DC, 20037. A larger quantity may also be requested for distribution to friends, physicians, HMOs, etc.

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Sonja Timmers, e-mail: nrsprntg@athenet.net
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